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What does 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE stand for?
What does 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE.
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1 BOY, 1 WVI, 1,, 1-50IA, 1-68 AR, 1., 1/12, 1/2NS, 1/4NS, 1/4WA
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What does 1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE mean?
- 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine
- MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a prodrug to the neurotoxin MPP+, which causes permanent symptoms of Parkinson's disease by destroying dopaminergic neurons in the substantia nigra of the brain. It has been used to study disease models in various animal studies. While MPTP itself has no psychoactive effects, the compound may be accidentally produced during the manufacture of MPPP, a synthetic opioid drug with effects similar to those of morphine and pethidine (meperidine). The Parkinson-inducing effects of MPTP were first discovered following accidental injection as a result of contaminated MPPP.
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