What does 4-HYDROXYCOUMARIN stand for?

What does 4-HYDROXYCOUMARIN mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: 4-HYDROXYCOUMARIN.

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3Z1, 3Z5, 3Z8, 3Z9, 3–DOF, 4, 4 & 20, 4 GIG, 4-8-6, 4-DR, 4-W, 40, 40' HQ, 400, 40003, 40004, 40006, 40007, 40008, 40009, 40010

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What does 4-HYDROXYCOUMARIN mean?

4-Hydroxycoumarin
4-Hydroxycoumarins are a class of vitamin K antagonist anticoagulant drug molecules derived from coumarin by adding a hydroxy group at the 4 position to obtain "4-hydroxycoumarin", then adding a large aromatic substituent at the 3-position. The large 3-position substituent is required for anticoagulant activity. The primary mechanism of the 4-hydroxycoumarin drugs is the inhibition of vitamin K epoxide reductase. These compounds are not direct antagonists of vitamin K, but rather act to deplete reduced vitamin K in tissues. For this reason vitamin K antagonizes their effect, and this has led to the loose terminology of vitamin K antagonism.

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"4-HYDROXYCOUMARIN." Abbreviations.com. STANDS4 LLC, 2014. Web. 30 Jul 2014. <http://www.abbreviations.com/4-HYDROXYCOUMARIN>.


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