What does CREB stand for?

What does CREB mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: CREB.

We've found a total of 7 definitions for CREB:

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CREB

cAMP Response Element Binding Protein

Medical » Human Genome

   
CREB

Cyclic-AMP Response Element Binding

Medical » Human Genome

   
CREB

Champion Parts, Inc.

Business » NASDAQ Symbols

   
CREB

Cairns Regional Electricity Board

Community

   
CREB

Cyclicamp Response Element Binding

Academic & Science » Chemistry

   
CREB

Clinical Research Ethics Board

Medical » Laboratory

   
CREB

CERN Reports Editorial Board

Academic & Science » Physics

   

What does CREB mean?

CREB
CREB is a cellular transcription factor. It binds to certain DNA sequences called cAMP response elements, thereby increasing or decreasing the transcription of the downstream genes. CREB was first described in 1987 as a cAMP-responsive transcription factor regulating the somatostatin gene. Genes whose transcription is regulated by CREB include: c-fos, the neurotrophin BDNF, tyrosine hydroxylase, and many neuropeptides. CREB is closely related in structure and function to CREM and ATF-1 proteins. CREB proteins are expressed in many animals, including humans. CREB has a well-documented role in neuronal plasticity and long-term memory formation in the brain. CREB has been shown to be integral in the formation of spatial memory. In recent experiments it has been demonstrated that CREB may possess therapeutic potential for patients that have Alzheimer's disease.

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