What does TUS stand for?

What does TUS mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: TUS.

We've found a total of 10 definitions for TUS:

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Tipta Uzmanlik Sinavi

International » Turkish


Tucson International Airport

Governmental » Transportation


The Usual Suspects

Community » Law & Legal


Tuscaloosa, Alabama

Regional » States


Tuskegee Institute

Academic & Science » Colleges & Universities


Tisfoon Ulterior Systems

Business » Companies & Firms


Tactical Unmanned System

Governmental » Military


Tucson International Airport, Tucson, Arizona USA

Regional » Airport Codes


Tearing Up Society

Community » Law & Legal





What does TUS mean?

Tus, also known as terminus utilization substance, is a protein that binds to terminator sequences and acts as a counter-helicase when it comes in contact with an advancing helicase. The bound Tus protein effectively halts DNA polymerase movement. Tus helps end DNA replication in prokaryotes. In E Coli, Tus binds to 10 closely related sites encoded in the chromosome. These sites bind 23 base-pairs. The 10 sites are called Ter sites, and are designated TerA, TerB, ..., TerJ. These binding sites are asymmetric, such that when a Tus-Ter complex is encountered by a replication fork from one direction, the complex is dissociated and replication continues. But when encountered from the other direction, the Tus-Ter complex provides a much larger kinetic barrier and halts replication. The multiple Ter sites in the chromosome are oriented such that the two oppositely moving replication forks are both stalled in the desired termination region. Bacillus subtilis utilize replication terminator protein instead of Tus.

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