| DEFC | Direct-Ethanol Fuel Cell | |
| DEFC | Dixhills Evangelical Free Church | |
| DEFC | Dixhills Evangelical Free Church | |
| DEFC | DeForest Evangelical Free Church | |
| DEFC | DeForest Evangelical Free Church | |
| DEFCON | Defense Readiness Condition | |
| DEFE | Differential Expression Feature Extraction | |
| DEFE | Driver Emotion Facial Expression | |
| DEFEAT | Diet Exercise Family Education Attitude and Thriving | |
| DEFEAT | Diet Exercise Family Education Attitude and Thriving | |
| defen | defence | |
| DEFEND | Defiance at the End | |
| DEFF | Department of Environment Forestry and Fisheries | |
| DEFF | Data Extractor Forensic Format | |
| DEFF | Design Evolution For the Future | |
| DEFG | Defogger | |
| DEFHR | Days End Farm Horse Rescue | |
| DEFI | Data Entry File Inquiry | |
| DEFI | Digital Electronic Fuel Injection | |
| DeFi | DèFi is a French term meaning " challenge ". | |
| DeFi | DèFi is a French term meaning " challenge ". | |
| DeFi | Decentralized Finance | |
| DEFINE | Dark Effort For Idiots Not Economics | |
| DEFL | DEFLect | |
| DEFL | Digital Enterprise Forum Lucerne |
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