What does UPR mean in Human Genome?
This page is about the meanings of the acronym/abbreviation/shorthand UPR in the Medical field in general and in the Human Genome terminology in particular.
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What does UPR mean?
- Unfolded Protein Response
- A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS.