What does UPR mean in Human Genome?

This page is about the meanings of the acronym/abbreviation/shorthand UPR in the Medical field in general and in the Human Genome terminology in particular.

Unfolded Protein Response

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What does UPR mean?

Unfolded Protein Response
A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS.

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"UPR." Abbreviations.com. STANDS4 LLC, 2016. Web. 24 Aug. 2016. <http://www.abbreviations.com/term/1426086>.