What does UPR mean in Physiology?

This page is about the meanings of the acronym/abbreviation/shorthand UPR in the Medical field in general and in the Physiology terminology in particular.

unfolded protein response

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Definition

What does UPR mean?

Unfolded Protein Response
A cellular response to environmental insults that cause disruptions in PROTEIN FOLDING and/or accumulation of defectively folded protein in the ENDOPLASMIC RETICULUM. It consists of a group of regulatory cascades that are triggered as a response to altered levels of calcium and/or the redox state of the endoplasmic reticulum. Persistent activation of the unfolded protein response leads to the induction of APOPTOSIS.

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"UPR." Abbreviations.com. STANDS4 LLC, 2014. Web. 19 Dec. 2014. <http://www.abbreviations.com/term/1435182>.


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