What does TYK mean in Human Genome?

This page is about the meanings of the acronym/abbreviation/shorthand TYK in the Medical field in general and in the Human Genome terminology in particular.

Tyrosine Kinase

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What does TYK mean?

Tyrosine kinase
A tyrosine kinase is an enzyme that can transfer a phosphate group from ATP to a protein in a cell. It functions as an "on" or "off" switch in many cellular functions. Tyrosine kinases are a subclass of protein kinase. The phosphate group is attached to the amino acid tyrosine on the protein. Tyrosine kinases are a subgroup of the larger class of protein kinases which attach phosphate groups to other amino acids. Phosphorylation of proteins by kinases is an important mechanism in communicating signals within a cell and regulating cellular activity, such as cell division. Protein kinases can become mutated, stuck in the "on" position, and cause unregulated growth of the cell, which is a necessary step for the development of cancer. Therefore, kinase inhibitors, such as imatinib, are often effective cancer treatments. Most tyrosine kinases have an associated protein tyrosine phosphatase, which removes the phosphate group.

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