| HOPE | Helpers Overcoming Problems Effectively | |
| HOPE | Home of Opportunity, Peace, and Education | |
| HOPE | Help Overcome Professional Exploitation | |
| HOPE | Help Our People Eat | |
| HOPE | Hands-On Preschool Education | |
| HOPE | Healing, Offering, Preserving, and Enriching | |
| HOPE | Housing Opportunities, Partnership, and Employment | |
| HOPE | Helping Our Pedestrians Everywhere | |
| HOPE | Honoring Our Professors Excellence | |
| HOPE | Helping Our People Endure | |
| HOPE | Homes Of Personal Encouragement | |
| HOPE | Home Opportunity, Prayer, and Education | |
| HOPE | Helping Other Parents Endure | |
| HOPE | Himalayan Outreach and Personal Evangelism | |
| HOPE | Health Organizer Plus Essentials | |
| HOPE | Help Our People Excel | |
| HOPE | Help Our Parents Educate | |
| HOPE | Home Ownership for People Everywhere | |
| HOPE | Honest, Orderly, and Peaceful Elections | |
| HOPE | Help and Opportunity to Pursue Education | |
| HOPE | Helping Other People Eat | |
| HOPE | Health Opportunity for People Everywhere | |
| HOPE | Helps On Personal Evaluation | |
| HOPE | Having Opportunity Provides Empowerment | |
| HOPE | Healing Of Past Emotions |
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