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| PRS | Polygenic Risk Score | |
| PRS | Pharmacy Regulatory Specialist | |
| PRS | Periodic Review Secretariat | |
| PRS | Pure Radio Sex | |
| PRS | Pierre Robin Sequence | |
| PRS | Pacific Retirement Services | |
| PRS | Professional Research Services | |
| PRS | Protocol Revision Subcommittee | |
| PRS | Pressure Regulating Stems | |
| PRS | Pivoting Retention Strap | |
| PRS | Passenger Reservation System | |
| PRS | Protocol Revisions Subcommittee | |
| PRS | Pedal Release System | |
| PRS | Passive Rear Steering | |
| PRS | Programmed Restraint System | |
| PRS | Panoz Racing School | |
| PRS | Panoz Racing Series | |
| PRS | Performance Review System | |
| PRS | Pacenote Rally Series | |
| PRS | Penske Racing Shocks | |
| PRS | Problematic Roadway Segments | |
| PRS | Portland Roadster Show | |
| PRS | Programme Service | |
| PRS | Philippine Rallycross Series | |
| PRS | Primary Restraint Systems |
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