| SIRS | Systemic inflammatory response syndrome | |
| SIRS | Scout International Relief Service | |
| SIRS | Scout International Relief Service | |
| SIRS | Side Impact Restraint System | |
| SIRS | Structure Inventory Records System | |
| SIRS | Stores Inventory Request System | |
| SIRSA | Special Industrial Radio Service Association | |
| SIRT | Sierra National Bank of Tehachapi (de-listed) | |
| SIRT | Self-Imposed Red Tape | |
| SIRT | Selective Internal Radiation Therapy | |
| SIRT | Service Issues Resolution Team | |
| SIRT | Shot Indicating Resetting Trigger | |
| SIRT | Serious Incident Response Team | |
| SIRT | Simultaneous Iterative Reconstruction Technique | |
| SIRT | Security Incident Response Team | |
| SIRT | Shot Indicating Reset Trigger | |
| SIRT | Shot Indicating and Resetting Trigger | |
| SIRT | Security Incident Response Team | |
| SIRT | System for Information Reference and Traceability | |
| SIRT | Special Incident Response Team | |
| SIRT | Staten Island Rapid Transit | |
| SIRT | Sagar Institute of Research & Technology | |
| SIRT | Sagar Institute of Research & Technology | |
| SIRT | Sagar Institute of Research & Technology | |
| SIRT | Selective Internal Radiation Therapy |
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