| SUPE | Superior Motorhome | |
| SUPE | Supercharger | |
| SUPE | Substance Use Prevention Education | |
| SUPE | Substance Use Prevention Education | |
| SUPE | Substance Use Prevention Education | |
| SUPE | Substance Use Prevention Education | |
| SUPEA | Service universitaire de psychiatrie de l'enfant et de l'adolescent | |
| SUPEC | Scale-Up and Post-Approval Changes | |
| SUPEC-IR | Scale-Up and Post-Approval Changes - Instant Release | |
| SUPER | Service Unique President Executive And Relationship | |
| SUPER | Students United Promoting Entertainment And Recreation | |
| SUPER | Special Unlimited Personal Electronic Resources | |
| SUPER | Special University Program To Encourage Recycling | |
| SUPER | Simplified Universal Player Encoder & Renderer | |
| SUPER | Simplified Universal Player Encoder Renderer | |
| SUPER | Spacious Useful Practical Efficient and Reasonable | |
| SUPER | Simplified Universal Player Encoder and Renderer | |
| SUPERB | Students United in Preserving Exploring and Researching Biodiversity | |
| SUPERB | State Underground Petroleum Environmental Response Bank | |
| SUPERB | State Underground Petroleum Environmental Response Bank | |
| SUPERB | State Underground Petroleum Environmental Response Bank | |
| SUPERB | Summer Undergraduate Program in Engineering Research at | |
| SUPERB | Summer Undergraduate Program in Engineering Research at | |
| SUPERBOCK | Some Uneducated Person Entertaining Random Boys On Chocolate Kills | |
| supercalifragilisticexpialidocious | extremely good(made popular in the 1964 children's film, "Mary Poppins") |
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