| U&C | Usual and Customary | |
| U&E | Urea & Electrolytes - blood test | |
| U&E | Urea & Electrolites (potassium, sodium, carbon dioxide, and chloride) | |
| U&ES | Urea and Electrolytes | |
| U&L | Upper And Lower | |
| U&LC | Uppercase and Lowercase | |
| U&LRA | Upper and Lower Radius Arms | |
| U&LW | Upper and Lower Wishbones | |
| U&M | Units & Measurements | |
| U&MNP | Ulnar And Median Nerve Palsy | |
| U&MPV | Utility and Multi Purpose Vehicle | |
| U&P | Username and Password | |
| U&R | Update and Restore | |
| U-ACH | UKC (United Kennel Club) Agility CHampion | |
| U-ACHX | UKC (United Kennel Club) Agility CHampion eXcellent | |
| U-AGI | UKC (United Kennel Club) AGility I | |
| U-AGII | UKC (United Kennel Club) AGility II | |
| U-BOOT | Universal Boot Loader | |
| U-CD | UKC (United Kennel Club) - Companion Dog | |
| U-CDX | UKC (United Kennel Club) - Companion Dog Excellent | |
| U-KISS | Ubiquitous Korean International Superstar | |
| U-NII | Unlicensed National Information Infrastructure | |
| U-NII | Unlicensed National Information Infrastructure | |
| U-SB | Unified S-Band | |
| U-UD | UKC (United Kennel Club) - Utility Dog |
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