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Acronyms that contain the term b-cell cll/lymphoma 2

What does b-cell cll/lymphoma 2 mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: b-cell cll/lymphoma 2.

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C

Academic & Science » Mathematics

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TCR

Medical » Physiology

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TCR

Medical » Human Genome

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TCR

Medical » Laboratory

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NSCLC

Medical » Oncology

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RBC

Medical » Laboratory

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PCNA

Medical » Laboratory

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WBC

Medical » Laboratory

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WBC

Medical » Human Genome

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WBC

Medical » Physiology

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NHL

Medical » Oncology

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SCC

Medical » Oncology

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VCAM

Medical » Laboratory

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FC

Governmental » Transportation

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BCL

Medical » Oncology

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NHL

Miscellaneous » Unclassified

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FACS

Medical » Laboratory

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SCLC

Medical » Oncology

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SCLC

Medical » Physiology

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RCC

Medical » Oncology

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FACS

Medical » Human Genome

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WBC

Medical » Oncology

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WBC

Medical » Physiology

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CAM

Medical » Human Genome

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BCR

Medical » Human Genome

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What does b-cell cll/lymphoma 2 mean?

B-cell CLL/lymphoma 2
Bcl-2, encoded by the BCL2 gene, is the founding member of the Bcl-2 family of regulator proteins that regulate cell death. Bcl-2 derives its name from B-cell lymphoma 2, as it is the second member of a range of proteins initially described in chromosomal translocations involving chromosomes 14 and 18 in follicular lymphomas. Bcl-2 orthologs have been identified in numerous mammals for which complete genome data are available. The two isoforms of Bcl-2, Isoform 1, also known as 1G5M, and Isoform 2, also known as 1G5O/1GJH, exhibit similar fold. However, results in the ability of these isoforms to bind to the BAD and BAK proteins, as well as in the structural topology and electrostatic potential of the binding groove, suggest differences in antiapoptotic activity for the two isoforms

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"b-cell cll/lymphoma 2." Abbreviations.com. STANDS4 LLC, 2018. Web. 21 Apr. 2018. <https://www.abbreviations.comserp.php?st=b-cell+cll%2Flymphoma+2>.

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