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Acronyms that contain the term defriend 

What does defriend mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: defriend.

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DEFN, DEFO, DEFOG, DEFRA, DEFRAG, DEFs, DEFSMAC, DEFT, DEFU, DEFY

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What does defriend mean?

defriend(Verb)
To remove from one's list of friends (e.g. on a social networking website).

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