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Acronyms that contain the term dolastatin 10
What does dolastatin 10 mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: dolastatin 10.
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What does dolastatin 10 mean?
- Dolastatin 10
- A pentapeptide originally isolated from the marine mollusk Dolabella auricularia with potential antineoplastic activity. Binding to tubulin, Dolastatin 10 inhibits microtubule assembly, resulting in the formation of tubulin aggregates and inhibition of mitosis. This agent also induces tumor cell apoptosis through a mechanism involving bcl-2, an oncoprotein that is overexpressed in some cancers. (NCI04)
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"dolastatin 10." Abbreviations.com. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.abbreviations.com/dolastatin%2010>.
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