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Acronyms that contain the term nicotinamide phosphoribosyltransferase
What does nicotinamide phosphoribosyltransferase mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: nicotinamide phosphoribosyltransferase.
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What does nicotinamide phosphoribosyltransferase mean?
- Nicotinamide phosphoribosyltransferase
- Nicotinamide phosphoribosyltransferase (NAmPRTase or NAMPT), formerly known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin for its extracellular form (eNAMPT), is an enzyme that in humans is encoded by the NAMPT gene. The intracellular form of this protein (iNAMPT) is the rate-limiting enzyme in the nicotinamide adenine dinucleotide (NAD+) salvage pathway that converts nicotinamide to nicotinamide mononucleotide (NMN) which is responsible for most of the NAD+ formation in mammals. iNAMPT can also catalyze the synthesis of NMN from phosphoribosyl pyrophosphate (PRPP) when ATP is present. eNAMPT has been reported to be a cytokine (PBEF) that activates TLR4, that promotes B cell maturation, and that inhibits neutrophil apoptosis.
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"nicotinamide phosphoribosyltransferase." Abbreviations.com. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.abbreviations.com/nicotinamide%20phosphoribosyltransferase>.
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