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Acronyms that contain the term p-anca 

What does p-anca mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: p-anca.

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P(E), P(J), P*, P,C,&H, P-A, P-BAND, P-BEST, P-Book, P-F, P-G

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What does p-anca mean?

P-ANCA
p-ANCA, or MPO-ANCA, or perinuclear anti-neutrophil cytoplasmic antibodies, are antibodies that stain the material around the nucleus of a neutrophil. They are a special class of anti-neutrophil cytoplasmic antibodies. This pattern occurs because the vast majority of the antigens targeted by ANCAs are highly cationic (Positively charged) at pH 7.00. During ethanol (pH ~7.0 in water) fixation, antigens which are more cationic migrate and localize around the nucleus, attracted by its negatively charged DNA content. Antibody staining therefore results in fluorescence of the region around the nucleus.

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