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Acronyms that contain the term udp-glucose 4-epimerase
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What does udp-glucose 4-epimerase mean?
- UDP-glucose 4-epimerase
- The enzyme UDP-glucose 4-epimerase (EC 5.1.3.2), also known as UDP-galactose 4-epimerase or GALE, is a homodimeric epimerase found in bacterial, fungal, plant, and mammalian cells. This enzyme performs the final step in the Leloir pathway of galactose metabolism, catalyzing the reversible conversion of UDP-galactose to UDP-glucose. GALE tightly binds nicotinamide adenine dinucleotide (NAD+), a co-factor required for catalytic activity.Additionally, human and some bacterial GALE isoforms reversibly catalyze the formation of UDP-N-acetylgalactosamine (UDP-GalNAc) from UDP-N-acetylglucosamine (UDP-GlcNAc) in the presence of NAD+, an initial step in glycoprotein or glycolipid synthesis.
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"udp-glucose 4-epimerase." Abbreviations.com. STANDS4 LLC, 2023. Web. 23 Sep. 2023. <https://www.abbreviations.com/udp-glucose%204-epimerase>.
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