What does H2A mean in Human Genome?

This page is about the meanings of the acronym/abbreviation/shorthand H2A in the Medical field in general and in the Human Genome terminology in particular.

Histone H2A

Histone H2A type 2-A is a protein that in humans is encoded by the HIST2H2AA3 gene. Histone H2A type 2-B is a protein that in humans is encoded by the HIST2H2AB gene. Histone H2A type 2-C is a protein that in humans is encoded by the HIST2H2AC gene. Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family.

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"H2A." Abbreviations.com. STANDS4 LLC, 2021. Web. 26 Jan. 2021. <https://www.abbreviations.com/term/1507559>.

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