What does E2F mean in Human Genome?

This page is about the meanings of the acronym/abbreviation/shorthand E2F in the Medical field in general and in the Human Genome terminology in particular.

A group of genes that codifies a family of transcription factors (TF) in higher eukaryotes

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Submitted by tirubuna on August 22, 2018

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Definition

What does E2F mean?

E2F
E2F is a group of genes that encodes a family of transcription factors (TF) in higher eukaryotes. Three of them are activators: E2F1, 2 and E2F3a. Six others act as suppressors: E2F3b, E2F4-8. All of them are involved in the cell cycle regulation and synthesis of DNA in mammalian cells. E2Fs as TFs bind to the TTTCCCGC (or slight variations of this sequence) consensus binding site in the target promoter sequence.

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"E2F." Abbreviations.com. STANDS4 LLC, 2024. Web. 25 Apr. 2024. <https://www.abbreviations.com/term/2016404>.

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