What does TRIF mean in Technology?

This page is about the meanings of the acronym/abbreviation/shorthand TRIF in the Computing field in general and in the Technology terminology in particular.

Technology Research Initiative Fund

Computing » Technology

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Definition

What does TRIF mean?

TRIF
TIR-domain-containing adapter-inducing interferon-β (TRIF) is an adapter in responding to activation of toll-like receptors (TLRs). It mediates the rather delayed cascade of two TLR-associated signaling cascades, where the other one is dependent upon a MyD88 adapter.Toll-like receptors (TLRs) recognize specific components of microbial invaders and activate an immune response to these pathogens. After these receptors recognize highly conserved pathogenic patterns, a downstream signaling cascade is activated in order to stimulate the release of inflammatory cytokines and chemokines as well as to upregulate the expression of immune cells. All TLRs have a TIR domain that initiates the signaling cascade through TIR adapters. Adapters are platforms that organize downstream signaling cascades leading to a specific cellular response after exposure to a given pathogen.

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"TRIF." Abbreviations.com. STANDS4 LLC, 2024. Web. 28 Mar. 2024. <https://www.abbreviations.com/term/338133>.

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