We've got 1 shorthand for heteroduplex analysis »
Acronyms that contain the term heteroduplex analysis
What does heteroduplex analysis mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: heteroduplex analysis.
Filter by:
Sort by:PopularityAlphabeticallyCategory
Term | Definition | Rating |
---|---|---|
HDA | heteroduplex analysis |
What does heteroduplex analysis mean?
- Heteroduplex analysis
- Heteroduplex analysis (HDA) is a method in biochemistry used to detect point mutations in DNA since 1992. Heteroduplexes are dsDNA molecules that have one or more mismatched pairs, on the other hand homoduplexes are dsDNA which are perfectly paired. This method of analysis depend up on the fact that heteroduplexes shows reduced mobility relative to the homoduplex DNA. heteroduplexes are formed between different DNA alleles. In a mixture of wild-type and mutant amplified DNA, heteroduplexes are formed in mutant alleles and homoduplexes are formed in wild-type alleles. There are two types of heteroduplexes based on type and extent of mutation in the DNA. Small deletions or insertion create bulge-type heteroduplexes which is stable and is verified by electron microscope. Single base substitutions creates more unstable heteroduplexes called bubble-type heteroduplexes, because of low stability it is difficult to visualize in electron microscopy. HDA is widely used for rapid screening of mutation of the 3 bp p.F508del deletion in the CFTR gene.
Know what is heteroduplex analysis? Got another good explanation for heteroduplex analysis? Don't keep it to yourself!
Still can't find the acronym definition you were looking for? Use our Power Search technology to look for more unique definitions from across the web!
Citation
Use the citation options below to add these abbreviations to your bibliography.
Style:MLAChicagoAPA
"heteroduplex analysis." Abbreviations.com. STANDS4 LLC, 2024. Web. 26 Apr. 2024. <https://www.abbreviations.com/heteroduplex%20analysis>.
Discuss these heteroduplex analysis abbreviations with the community:
Report Comment
We're doing our best to make sure our content is useful, accurate and safe.
If by any chance you spot an inappropriate comment while navigating through our website please use this form to let us know, and we'll take care of it shortly.
Attachment
You need to be logged in to favorite.
Log In