What does NLRP mean in Unclassified?

This page is about the meanings of the acronym/abbreviation/shorthand NLRP in the Miscellaneous field in general and in the Unclassified terminology in particular.

Northwest Liver Research Program

Miscellaneous » Unclassified

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Definition

What does NLRP mean?

NLRP
NLRP (Nucleotide-binding oligomerization domain, Leucine rich Repeat and Pyrin domain containing), also abbreviated as NALP, is a type of NOD-like receptor. NLRP proteins are part of the innate immunity and detect conserved pathogen characteristics such as peptidoglycan. It is thought that NLRP proteins sense inherent danger, and link this with microbial products, creating a response under the concept of the inflammasome including K+ efflux and caspase 1 activation. NLRP is also known to be associated with a number of hereditary diseases. Research suggests NLRP proteins may be involved in combating retroviruses in gametes. Currently there are at least 13 known human NALP genes named as NALP1 through NALP13.

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"NLRP." Abbreviations.com. STANDS4 LLC, 2024. Web. 5 May 2024. <https://www.abbreviations.com/term/1732369>.

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