What does vWF mean in Medical?

This page is about the meanings of the acronym/abbreviation/shorthand vWF in the field in general and in the Medical terminology in particular.

von Willebrand factor

. vWF is a multimeric glycoprotein encoded for by gene map locus 12p13.31.[1]It is made in the endothelium and stored in Weibel-Palade bodies. It has two main functions: •It assists in platelet plug formation by attracting circulating platelets to the site of damage. •It binds to coagulation factor VIII preventing its clearance from the plasma.

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Submitted by Dr.Rupayan Talukder on January 29, 2018

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Definition

What does vWF mean?

Von Willebrand factor
Von Willebrand factor (VWF) (German: [fɔn ˈvɪləbʁant]) is a blood glycoprotein involved in hemostasis, specifically, platelet adhesion. It is deficient and/or defective in von Willebrand disease and is involved in many other diseases, including thrombotic thrombocytopenic purpura, Heyde's syndrome, and possibly hemolytic–uremic syndrome. Increased plasma levels in many cardiovascular, neoplastic, metabolic (e.g. diabetes), and connective tissue diseases are presumed to arise from adverse changes to the endothelium, and may predict an increased risk of thrombosis.

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"vWF." Abbreviations.com. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.abbreviations.com/term/1971507>.

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