| DESI | Developing Ecologically Sustainable Industry | |
| DESI | Doctors Earn Significant Incomes | |
| DESI | Discovery of Electronically Stored Information | |
| DESI | Duty to Empathize Sterilize and Immunize | |
| DESI | Desorption Electro Spray Ionisation | |
| DESI | Drug Efficacy Study Implementation | |
| desig | designation | |
| DESIG | DESIGnate | |
| DESIGAREA | DESIGnated AREA Message | |
| DESIGN | Diving Equipment Systems Inspection Guidance Note | |
| DesignCon | Semiconductor and Electronic Design Conference | |
| DesignCon | Semiconductor and Electronic Design Conference | |
| DESIRE | Directory of European Information Security Standard Requirements | |
| DESIRE | Development of European Service for Information on Research and Education | |
| DESIRE | Decision Effort Study Integrity Rehearse Excellence | |
| DESIS | DLR Earth Sensing Imaging Spectrometer | |
| DESK | Donate Educational Supplies for Kids (San Angelo, TX) | |
| DESK | Deadly Epidemic Student Killer | |
| DESL | Distributed Electrical Systems Laboratory | |
| DESL | Discover e Solutions Ltd | |
| DESL | DNA Extraction and Staging Laboratory | |
| DESL | Distributed Electrical Systems Laboratory | |
| DESL | Digital and Embedded Systems Lab | |
| DESL | Digital Embedded Systems Lab | |
| DESM | Diploma in Engineering Systems and Management |
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