| HPTD | High Point, Thomasville and Denton Railroad | |
| HPTDC | High Performance Time to Digital Converter | |
| HPTE | High Performance Transportation Enterprise | |
| HPTET | Himachal Pradesh Teacher Eligibility Test | |
| HPTF | Hydraulic and Power Transmission Fluids | |
| HPTh | History of Political Thought | |
| HPTH | Hyperparathyroidism | |
| HPTI | High Potential Trait Indicator | |
| HPTI | Hittle Power Technologies Inc | |
| HPTI | High Performance Technologies Incorporated | |
| HPTI | Hypnosis Practitioner Training Institute | |
| HPTI | High Potential Traits Indicator | |
| HPTI | Highly Purified Therapeutic Immunoglobulins | |
| HPTI | Human Performance Training Institute | |
| HPTL | High Payoff Target List | |
| HPTL | Human Peripheral T Lymphocytes | |
| HPTL | High Priority Threat List | |
| HPTL | High Power Target Laboratory | |
| HPTL | High Pressure Tritium Laboratory | |
| HPTL | Hidden Propositional Temporal Logic | |
| HPTL | High Priority Target List | |
| HPTL | High-Payoff Target List | |
| HPTL | High Power Transmission Lines | |
| HPTLC | High Performance Thin Layer Chromatography | |
| HPTLC | High Performance Thin Layer Chromatographic |
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