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| MEC | Minimal Effective Concentration | |
| MEC | Mobile Engagement Center | |
| MEC | Mountain Equipment Company | |
| MEC | Microsoft Exchange Conference | |
| MEC | Mayville Engineering Co | |
| MEC | Manufacturing Exploration and Combat | |
| MEC | Materials Energy and Constructions | |
| MEC | Minimum Essential Coverage | |
| MEC | Medical Education Collaborative | |
| MEC | Merrimack Education Center | |
| MEC | Metalsmith Chief Petty Officer | |
| MEC | Mobile Edge Computing | |
| MEC | Microsoft Experience Center | |
| MEC | Massively Empowered Classrooms | |
| MEC | Marine Employees Commission | |
| MEC | Malaysia Electric Corporation | |
| MEC | Marianas Energy Corporation | |
| MEC | Mutual Execution of Contract | |
| MEC | Mediterranean Exploration Company | |
| MEC | Minimum Essential Coverage | |
| MEC | Mathematics Education Collaborative | |
| MEC | Mathematics Education Collaborative | |
| MEC | Mechanical Electronics and Computing | |
| MEC | Mechanical Electronics and Computing | |
| MEC | Maine Central Railroad (Pan Am Railways) |
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