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What does GENOCOPY stand for?
What does GENOCOPY mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: GENOCOPY.
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What does GENOCOPY mean?
- Genocopy
- Genocopy is a trait that is a phenotypic copy of a genetic trait but is caused by a different genotype. When a genetic mutation or genotype in one locus results in a phenotype similar to one that is known to be caused by another mutation or genotype in another locus, it is said to be a genocopy. However, genocopies may also be referred to as "genetic mimics", in which the same mutation or specific genotype can result in two unique phenotypes in two different patients. The term “Genocopy” was coined by Dr. H. Nachstheim in 1957, in which he discusses “false” phenocopies. In comparison to when a phenotype is the result of an environmental condition that had the same effect as a previously known genetic factor such as mutation. While offspring may inherit specific mutations or genotypes that result in genocopies, phenocopies are not heritable. Two types of elliptocytosis that are genocopies of each other, but are distinguished by the fact that one is linked to the Rh blood group locus and the other is not. The way to distinguish a recessive genocopy from a phenotype caused by a different allele would be by carrying out a test cross, breeding the two together, if they F1 hybrid segregates 1:2:1 then we can determine that it was a genocopy.
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