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What does TIRAP stand for?
What does TIRAP mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: TIRAP.
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What does TIRAP mean?
- TIRAP
- TIRAP is an adapter molecule associated with toll-like receptors. The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants; however, not all variants have been fully described.
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"TIRAP." Abbreviations.com. STANDS4 LLC, 2024. Web. 22 Sep. 2024. <https://www.abbreviations.com/TIRAP>.
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