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Acronyms that contain the term carbocyclic nucleoside
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What does carbocyclic nucleoside mean?
- Carbocyclic nucleoside
- Carbocyclic nucleosides (also referred to as carbanucleosides) are nucleoside analogues in which a methylene group has replaced the oxygen atom of the furanose ring. These analogues have the nucleobase attached at a simple alkyl carbon rather than being part of a hemiaminal ether linkage. As a result, they have increased chemical stability. They also have increased metabolic stability because they are unaffected by phosphorylases and hydrolases that cleave the glycosidic bond between the nucleobase and furanose ring of nucleosides. They retain many of the biological properties of the original nucleosides with respect to recognition by various enzymes and receptors. Carbocyclic nucleosides were originally limited to a five-membered ring system, matching the ring-size of the nucleosides; however, this term has been broadened to three-, four-, and six-membered rings.
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"carbocyclic nucleoside." Abbreviations.com. STANDS4 LLC, 2024. Web. 30 May 2024. <https://www.abbreviations.com/carbocyclic%20nucleoside>.
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