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Acronyms that contain the term homogentisate 1,2-dioxygenase
What does homogentisate 1,2-dioxygenase mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: homogentisate 1,2-dioxygenase.
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What does homogentisate 1,2-dioxygenase mean?
- Homogentisate 1,2-dioxygenase
- Homogentisate 1,2-dioxygenase (homogentisic acid oxidase, homogentisate oxidase, homogentisicase) is an enzyme which catalyzes the conversion of homogentisate to 4-maleylacetoacetate. Homogentisate 1,2-dioxygenase or HGD is involved in the catabolism of aromatic rings, more specifically in the breakdown of the amino acids tyrosine and phenylalanine. HGD appears in the metabolic pathway of tyrosine and phenylalanine degradation once the molecule homogentisate is produced. Homogentisate reacts with HGD to produce maleylacetoacetate, which then is further used in the metabolic pathway. HGD requires the use of Fe2+ and O2 in order to cleave the aromatic ring of homogentisate.
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