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Acronyms that contain the term janus kinase
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What does janus kinase mean?
- Janus kinase
- Janus kinase (JAK) is a family of intracellular, non-receptor tyrosine kinases that transduce cytokine-mediated signals via the JAK-STAT pathway. They were initially named "just another kinase" 1 and 2 (since they were just two of many discoveries in a PCR-based screen of kinases), but were ultimately published as "Janus kinase". The name is taken from the two-faced Roman god of beginnings, endings and duality, Janus, because the JAKs possess two near-identical phosphate-transferring domains. One domain exhibits the kinase activity, while the other negatively regulates the kinase activity of the first.
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"janus kinase." Abbreviations.com. STANDS4 LLC, 2024. Web. 4 Jun 2024. <https://www.abbreviations.com/janus%20kinase>.
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