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Acronyms that contain the term succinylation
What does succinylation mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: succinylation.
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What does succinylation mean?
- Succinylation
- Succinylation is a posttranslational modification where a succinyl group (-CO-CH2-CH2-CO2H) is added to a lysine residue of a protein molecule. This modification is found in many proteins, including histones. The potential role of succinylation is under investigation, but as addition of succinyl group changes lysine's charge from +1 to −1 (at physiological pH) and introduces a relatively large structural moiety (100 Da), bigger than acetylation (42 Da) or methylation (14 Da), it is expected to lead to more significant changes in protein structure and function.By analogy to acetylation, it has been suggested that succinyl-CoA is the cofactor of enzyme-mediated lysine succinylation.
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"succinylation." Abbreviations.com. STANDS4 LLC, 2024. Web. 5 Jun 2024. <https://www.abbreviations.com/succinylation>.
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