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Acronyms that contain the term Body Surface Area
What does Body Surface Area mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: Body Surface Area.
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What does Body Surface Area mean?
- Body surface area
- In physiology and medicine, the body surface area is the measured or calculated surface of a human body. For many clinical purposes BSA is a better indicator of metabolic mass than body weight because it is less affected by abnormal adipose mass. Nevertheless, there have been several important critiques of the use of BSA in determining the dosage of medications with a narrow therapeutic index like many chemotherapy medications. Typically there is a 4-10 fold variation in cytotoxic drug clearance between individuals due to differing activity of drug elimination processes related to genetic and environmental factors. This can lead to significant overdosing and even more perniciously to underdosing. It is also thought to be a distorting factor in Phase I and II trials that may result in potentially helpful medications being prematurely rejected. The trend to personalized medicine is one approach to counter this weakness. Estimation of BSA is simpler than many measures of volume.
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"Body Surface Area." Abbreviations.com. STANDS4 LLC, 2024. Web. 1 May 2024. <https://www.abbreviations.com/Body%20Surface%20Area>.
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