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Acronyms that contain the term VPG
What does VPG mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: VPG.
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What does VPG mean?
- VPg
- VPg is a protein that is covalently attached to the 5′ end of positive strand viral RNA and acts as a primer during RNA synthesis in a variety of virus families including Picornaviridae and Caliciviridae. The primer activity of VPg occurs when the protein becomes uridylylated, providing a free hydroxyl that can be extended by the virally encoded RNA-dependent RNA polymerase. Aside from functioning as a primer, VPg also has a role in translation initiation by acting like a 5' mRNA cap. VPg was first described in initial investigations of poliovirus RNA as a protein covalently attached to the 5' end of the genome. and later seen in caliciviruses.
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