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Acronyms that contain the term adenosylhomocysteinase
What does adenosylhomocysteinase mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: adenosylhomocysteinase.
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What does adenosylhomocysteinase mean?
- Adenosylhomocysteinase
- Adenosylhomocysteinase (EC 3.3.1.1, S-adenosylhomocysteine synthase, S-adenosylhomocysteine hydrolase, adenosylhomocysteine hydrolase, S-adenosylhomocysteinase, SAHase, AdoHcyase) is an enzyme that converts S-adenosylhomocysteine to homocysteine and adenosine. This enzyme catalyses the following chemical reaction S-adenosyl-L-homocysteine + H2O ⇌ L-homocysteine + adenosineThe enzyme contains one tightly bound NAD+ per subunit. The mechanism involves dehydrogenative oxidation of the 3'-OH of the ribose. The resulting ketone is susceptible to α-deprotonation. The resulting carbanion eliminates thiolate. The a,b-unsaturated ketone is then hydrated, and the ketone is reduced by the NADH.
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