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Acronyms that contain the term axicabtagene ciloleucel 

What does axicabtagene ciloleucel mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: axicabtagene ciloleucel.

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What does axicabtagene ciloleucel mean?

Axicabtagene ciloleucel
Axicabtagene ciloleucel, sold under the brand name Yescarta, is a treatment for large B-cell lymphoma that has failed conventional treatment. T cells are removed from a person with lymphoma and genetically engineered to produce a specific T-cell receptor. The resulting chimeric antigen receptor T cells (CAR-Ts) that react to the cancer are then given back to the person to populate the bone marrow. Axicabtagene treatment carries a risk for cytokine release syndrome (CRS) and neurological toxicities.Due to CD19 is a pan-B cell marker, the T-cells that are engineered to target CD19 receptors on the cancerous B cells also influence normal B cells, except some plasma cells.

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