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Acronyms that contain the term base excision repair
What does base excision repair mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: base excision repair.
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What does base excision repair mean?
- Base excision repair
- In biochemistry and genetics, base excision repair is a cellular mechanism that repairs damaged DNA throughout the cell cycle. It is responsible primarily for removing small, non-helix-distorting base lesions from the genome. The related nucleotide excision repair pathway repairs bulky helix-distorting lesions. BER is important for removing damaged bases that could otherwise cause mutations by mispairing or lead to breaks in DNA during replication. BER is initiated by DNA glycosylases, which recognize and remove specific damaged or inappropriate bases, forming AP sites. These are then cleaved by an AP endonuclease. The resulting single-strand break can then be processed by either short-patch or long-patch BER.
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"base excision repair." Abbreviations.com. STANDS4 LLC, 2024. Web. 6 May 2024. <https://www.abbreviations.com/base%20excision%20repair>.
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