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Acronyms that contain the term cleavage and polyadenylation specificity factor
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What does cleavage and polyadenylation specificity factor mean?
- Cleavage and polyadenylation specificity factor
- Cleavage and polyadenylation specificity factor (CPSF) is involved in the cleavage of the 3' signaling region from a newly synthesized pre-messenger RNA (pre-mRNA) molecule in the process of gene transcription. It is the first protein to bind to the signaling region near the cleavage site of the pre-mRNA, to which the poly(A) tail will be added by polynucleotide adenylyltransferase. The upstream signaling region has the canonical nucleotide sequence AAUAAA, which is highly conserved across the vast majority of pre-mRNAs. A second downstream signaling region, located on the portion of the pre-mRNA that is cleaved before polyadenylation, consists of a GU-rich region required for efficient processing.
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"cleavage and polyadenylation specificity factor." Abbreviations.com. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.abbreviations.com/cleavage%20and%20polyadenylation%20specificity%20factor>.
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