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Acronyms that contain the term first pass effect 

What does first pass effect mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: first pass effect.

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What does first pass effect mean?

First pass effect
The first pass effect (also known as first-pass metabolism or presystemic metabolism) is a phenomenon of drug metabolism whereby the concentration of a drug, specifically when administered orally, is greatly reduced before it reaches the systemic circulation. It is the fraction of drug lost during the process of absorption which is generally related to the liver and gut wall.

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