Acronyms that contain the term oxybutynin 

Oxybutynin

Oxybutynin is an anticholinergic medication used to relieve urinary and bladder difficulties, including frequent urination and inability to control urination, by decreasing muscle spasms of the bladder. It competitively antagonizes the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor. It also has direct spasmolytic effects on bladder smooth muscle as a calcium antagonist and local anesthetic, but at concentrations far above those used clinically. It is available orally in generic formulation or as the brand-names Ditropan, Lyrinel XL, or Ditrospam, as a transdermal patch under the brand name Oxytrol, and as a topical gel under the brand name Gelnique. Oxybutynin is also a possible treatment of hyperhidrosis. A 2009 Weill Cornell Medical College study concluded that patients switched to generic oxybutynin experienced a degradation in therapeutic value: "When we looked at changes in [prostate-specific antigen] levels among men on Avodart switched to the generic formulation, we saw a greater than 0.75 ng/mL increase at 3 months in 34% of men. That is an increase that would ordinarily trigger a biopsy, but I put them back on the brand-name drug. The PSA came down in all cases, and none of them needed a biopsy", Steven A. Kaplan said of the findings.

see more »