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Acronyms that contain the term spiperone
What does spiperone mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: spiperone.
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SPINTCOM, SPINTCOMM, SPINZ, SPION, SPIP, SPIR, SPIRAL, SPIRE, SPIREP, SPIRIT
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What does spiperone mean?
- Spiperone
- Spiperone is a psychoactive drug and research chemical belonging to the butyrophenone chemical class. It functions as a 5-HT1A, 5-HT2A, 5-HT7, and D2 receptor antagonist, and has been used to identify these receptors when labeled with tritium. It has negligible affinity for the 5-HT2C receptor. Additionally, spiperone was identified by compound screening to be an activator of Ca2+ activated Cl- channels, thus a potential target for therapy of cystic fibrosis. N-Methylspiperone is a derivate of spiperone that is used to study the dopamine and serotonin neurotransmitter system. Labeled with the radioisotope carbon-11, it can be used for positron emission tomography.
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