What does KSS mean in Physiology?
This page is about the meanings of the acronym/abbreviation/shorthand KSS in the Medical field in general and in the Physiology terminology in particular.
Kearns–Sayre Syndrome
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Submitted by paul8539 on March 9, 2013
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Definition
What does KSS mean?
- Kearns–Sayre syndrome
- Kearns–Sayre syndrome also known as oculocraniosomatic disease or Oculocraniosomatic neuromuscular disease with ragged red fibers is a mitochondrial myopathy with a typical onset before 20 years of age. KSS is a more severe syndromic variant of chronic progressive external ophthalmoplegia, a syndrome that is characterized by isolated involvement of the muscles controlling eyelid movement, and those controlling eye movement. This results in ptosis and ophthalmoplegia respectively. KSS involves a triad of the already described CPEO, as well as bilateral pigmentary retinopathy, and cardiac conduction abnormalities. Other areas of involvement can include cerebellar ataxia, proximal muscle weakness, deafness, diabetes mellitus, growth hormone deficiency, hypoparathyroidism, or other endocrinopathies. In both of these diseases, muscle involvement may begin unilateral but always develops into a bilateral deficit, and the course is progressive. This discussion is limited specifically to the more severe and systemically involved variant; KSS
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