What does MGUS mean in Human Genome?
This page is about the meanings of the acronym/abbreviation/shorthand MGUS in the Medical field in general and in the Human Genome terminology in particular.
Submitted by paul8539 on December 6, 2009
Translation
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Definition
What does MGUS mean?
- Monoclonal gammopathy of undetermined significance
- Monoclonal gammopathy of undetermined significance (MGUS) is a plasma cell dyscrasia in which plasma cells or other types of antibody-producing cells secrete a myeloma protein, i.e. an abnormal antibody, into the blood; this abnormal protein is usually found during standard laboratory blood or urine tests. MGUS resembles multiple myeloma and similar diseases, but the levels of antibodies are lower, the number of plasma cells (white blood cells that secrete antibodies) in the bone marrow is lower, and it rarely has symptoms or major problems. However, since MGUS can lead to multiple myeloma, which develops at the rate of about 1.5% a year, or other symptomatic conditions, yearly monitoring is recommended. The progression from MGUS to multiple myeloma usually involves several steps. In rare cases, it may also be related with a slowly progressive symmetric distal sensorimotor neuropathy.
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"MGUS." Abbreviations.com. STANDS4 LLC, 2024. Web. 24 Sep. 2024. <https://www.abbreviations.com/term/82037>.
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