What does RORA mean in Unclassified?

This page is about the meanings of the acronym/abbreviation/shorthand RORA in the Miscellaneous field in general and in the Unclassified terminology in particular.

related Orphan Receptor Alpha

Miscellaneous » Unclassified

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Definition

What does RORA mean?

RORA
RAR-related orphan receptor alpha (RORα), also known as NR1F1 (nuclear receptor subfamily 1, group F, member 1) is a nuclear receptor that in humans is encoded by the RORA gene. RORα participates in the transcriptional regulation of some genes involved in circadian rhythm. In mice, RORα is essential for development of cerebellum through direct regulation of genes expressed in Purkinje cells. It also plays an essential role in the development of type 2 innate lymphoid cells (ILC2) and mutant animals are ILC2 deficient. In addition, although present in normal numbers, the ILC3 and Th17 cells from RORα deficient mice are defective for cytokine production.

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"RORA." Abbreviations.com. STANDS4 LLC, 2024. Web. 5 May 2024. <https://www.abbreviations.com/term/1622160>.

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