What does POLI mean in IT?
This page is about the meanings of the acronym/abbreviation/shorthand POLI in the Computing field in general and in the IT terminology in particular.
Submitted by S4Bot on November 13, 2022
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Definition
What does POLI mean?
- POLI
- DNA polymerase iota is an enzyme that in humans is encoded by the POLI gene. It is found in higher eukaryotes, and is believed to have arisen from a gene duplication from Pol η. Pol ι, is a Y family polymerase that is involved in translesion synthesis. It can bypass 6-4 pyrimidine adducts and abasic sites and has a high frequency of wrong base incorporation. Like many other Y family polymerases Pol ι, has low processivity, a large DNA binding pocket and doesn't undergo conformational changes when DNA binds. These attributes are what allow Pol ι to carry out its task as a translesion polymerase. Pol ι only uses Hoogsteen base pairing, during DNA synthesis, it will add adenine opposite to thymine in the syn conformation and can add both cytosine and thymine in the anti conformation across guanine, which it flips to the syn conformation.
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"POLI." Abbreviations.com. STANDS4 LLC, 2024. Web. 5 May 2024. <https://www.abbreviations.com/term/2659853>.
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