What does COMT mean in Unclassified?
This page is about the meanings of the acronym/abbreviation/shorthand COMT in the Miscellaneous field in general and in the Unclassified terminology in particular.
Catechol O Methyltransferase Treating
Submitted by S4Bot on January 15, 2024
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Definition
What does COMT mean?
- comt
- Catechol-O-methyltransferase (COMT; EC 2.1.1.6) is one of several enzymes that degrade catecholamines (neurotransmitters such as dopamine, epinephrine, and norepinephrine), catecholestrogens, and various drugs and substances having a catechol structure. In humans, catechol-O-methyltransferase protein is encoded by the COMT gene. Two isoforms of COMT are produced: the soluble short form (S-COMT) and the membrane bound long form (MB-COMT). As the regulation of catecholamines is impaired in a number of medical conditions, several pharmaceutical drugs target COMT to alter its activity and therefore the availability of catecholamines. COMT was first discovered by the biochemist Julius Axelrod in 1957.
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"COMT." Abbreviations.com. STANDS4 LLC, 2024. Web. 26 Sep. 2024. <https://www.abbreviations.com/term/2697311>.
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