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What does CCL4 stand for?
What does CCL4 mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: CCL4.
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What does CCL4 mean?
- CCL4
- Chemokine (C-C motif) ligands 4 (also CCL4) previously known as macrophage inflammatory protein (MIP-1β), is a protein which in humans is encoded by the CCL4 gene. CCL4 belongs to a cluster of genes located on 17q11-q21 of the chromosomal region. Identification and localization of the gene on the chromosome 17 was in 1990 although the discovery of MIP-1 was initiated in 1988 with the purification of a protein doublet corresponding to inflammatory activity from supernatant of endotoxinstimulated murine macrophages. At that time, it was also named as "macrophage inflammatory protein-1" (MIP-1) due to its inflammatory properties.CCL4 is a small cytokine that belongs to the CC chemokine subfamily. CCL4 is being secreted under mitogenic signals and antigens and hereby acts as a chemoattractant for natural killer cells, monocytes and various other immune cells in the site of inflamed or damaged tissue.
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"CCL4." Abbreviations.com. STANDS4 LLC, 2024. Web. 29 Apr. 2024. <https://www.abbreviations.com/CCL4>.
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