What does PIGA stand for?
What does PIGA mean? This page is about the various possible meanings of the acronym, abbreviation, shorthand or slang term: PIGA.
What does PIGA mean?
- Phosphatidylinositol N-acetylglucosaminyltransferase subunit A is an enzyme that in humans is encoded by the PIGA gene. This gene encodes a protein required for synthesis of N-acetylglucosaminyl phosphatidylinositol, the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been characterized.